In Vitro DMPK & Toxicology Services

In Vitro DMPK Services

Invitrocue provides Cytochrome 450 (CYP450) induction/inhibition assay with cryo-preserved human hepatocytes and/or HepaCur fresh human hepatocytes.

  • CYP 450 induction
  • CYP 450 inhibition
  • Time dependent inhibition
  • Drug-drug interactions
  • Metabolite profiling

In Vitro toxicology services

Invitrocue provides comprehensive in vitro toxicology and safety pharmacology services to assess drug safety profiles early in the discovery process.

  • Oxidative stress reporter assay
  • Acyl glucuronide measurement
  • Cell viability
  • ATP content
  • Cell leakage
  • Cell proliferation
  • Resazurin
  • Steatosis
  • Nile red