Invivocue's HiMice
Invivocue was formed as a joint venture between Invitrocue, an innovative life sciences company providing in vitro liver models for drug toxicology testing, as well as 3D patient-derived organoid technology for personalised oncology, and Dr Chen Qing Feng, a Principal Investigator at A*STAR Singapore, Institute of Molecular and Cell Biology, whose research expertise focused on humanised mouse models for various disease applications.
Customization
Invivocue’s proprietary HiMice are a humanised mouse model with a stably reconstituted human immune system. As HiMice express the human immune system, they are an ideal in vivo animal model for research in human immunology, oncology, inflammation and infectious diseases.
Available customization:
| Cytokine Plasmids | Function |
| IL-15 | Improve T-cell and NK-cell differentiation and proliferation |
| GM-CSF | Improved granulocyte, monocyte, macrophage and eosinophils differentiation |
| IL-4 | Increased T and B lymphocyte proliferation |
| IL-3 | Improved proliferation of a broad range of hematopoietic cell types |
| M-CSF | Improved macrophage differentiation and proliferation |
| IL-7 | Increase T-cell development |
